Projects & Publications

Alfred Brain Tumour Bio-databank

The key to successful biobanking is collaboration between patients, families, treating clinicians and the scientists who perform research. These features are exemplified in the Alfred Brain Tumour Bio-databank (ABTB).

In one year, The Alfred Brain Tumour Bio-databank has consented over 100 patients with accompanying clinical information, tissue and blood donation. The ABTB collection will enable researchers to study the molecular and genetic features underlying the development of brain cancer and correlate with how they respond to different treatments, helping to pave the path to personalised therapy and a better outcome for patients affected by the disease.

Select publications:

1. A Simple and Reliable Protocol for the Preparation and Culturing of Fresh Surgically Resected Human Glioblastoma Tissue. 
Kan LK, Drummond KJ, Hunn M, et al., Methods Protoc. 2020. doi:10.3390/mps3010011

2. Blood Biomarkers of Glioma in Response Assessment Including Pseudoprogression and Other Treatment Effects: A Systematic Review.
Raza, IJ, Tingate, CA, Gkolia, P,  et al., Front. Oncol. 2020. doi:org/10.3389/fonc.2020.01191

3. Stereotactic radiosurgery for managing brain metastases in Victoria, 2012-2017 
Ong WL, Kang TMJ, Ratnayake G, et al., Medical Journal of Australia. 2020. doi:org/10.5694/mja2.50573

4. The role of microglia and P2X7 receptors in gliomas. Journal of Neuroimmunology
Kan LK, Williams D, Drummond KJ, et al., Journal of Neuroimmunology. 2019. doi:10.1016/j.jneuroim.2019.04.010

5. Data Sets for the Reporting of Tumors of the Central Nervous System
Louis DN, Wesseling P, Brandner S, et al., Arch Pathol Lab Med. 2019. doi:10.5858/arpa.2018-0565-OA